Neurological Complications after Pertussis Vaccine. The Enigma Is Still Here

Neurological complications of pertussis inoculation.

Kulenkampff, M., Schwartzman, J. S., and Wilson, J. (1974). Archives of Disease in Childhood, 49, 46. Neurological complications of pertussis inoculation. Findings are presented in 36 children, seen in the past 11 years, who are believed to have suffered from neurological complications of pertussis inoculation (given as triple vaccine). The clustering of complications in the first 24 hours afte...

Complications of Pe Rtussis Immunization Neurological Complications of Pertussis Immunization

Since Madsen (1933) first drew attention to the possibility of serious consequences following active immunization against whooping-cough, reports of neurological sequelae of such immunization have come from various parts of the world. These sequelae (post-inoculation poliQmyelitis is not being considered here) have ranged from transient convulsions with complete recovery to gross crippling, men...

Neurological complications after liver transplantation

This was a single-centre, prospective study to assess the frequency of neurological complications and their impact on prolonged hospitalization in 137 liver transplant patients presenting between September 1997 and June 2010. Neurological complications were seen in 22 (16%) patients during their postoperative stay in the intensive care unit. Complications included new-onset, recurrent headache...

Pertussis toxin is required for pertussis vaccine encephalopathy.

A mouse model for encephalopathy induced by pertussis immunization has been described; it has features that closely resemble some of the severe reactions, including seizures and a shock-like state leading to death, occasionally seen after administration of Bordetella pertussis (whooping cough) vaccine. Susceptibility to encephalopathy maps to genes of the major histocompatibility complex and co...

Fournier's gangrene, still an enigma.